Beyond Amorphous Solid Dispersion: Novel Applications in Pharmaceutical Spray Drying Executive Summary
Abstract: Spray drying has evolved beyond amorphous solid dispersions to become a scalable, versatile manufacturing platform for small molecules, peptides, biologics, and emerging modalities. This executive summary explores how advances in spray drying technology, modeling, automation, and process analytics are addressing long鈥憇tanding challenges in bioavailability, stability, and commercial scale鈥憉p. Through real鈥憌orld examples and a focus on quality鈥慴y鈥慸esign, simulation, and digitalization, the piece highlights how spray drying can accelerate development timelines, improve manufacturability, and support the transition to continuous pharmaceutical manufacturing.